UROLiTHin A

Urolithin A is a metabolic product of the ellagitannins prevalent in pomegranate, red and black berries, as well as other pigmented fruits. Ellagitannins are metabolized by intestinal microorganisms to ellagic acid, which is the immediate precursor of the family of urolithins. Urolithin A may help protect against cellular damage caused by inflammation and reactive oxygen species (ROS) Mitochondrial health Urolithin A may improve mitochondrial function and increase mitophagy, which can help with cellular health. Muscle health Urolithin A may promote muscle protein synthesis and growth, and help with muscle atrophy helps with weight loss by improving insulin sensitivity and reducing inflammation and fatty liver. Urolithin A is a metabolite produced by the gut microbiota when ellagic acid and ellagitannins are consumed in food. These compounds are found in berries, nuts, and pomegranate. However, only about 40% of people can naturally convert these compounds into UA at meaningful levels.Experimental models consistently show that UA increases mitophagy and mitochondrial function and blunts excessive inflammatory responses. Urolithin A increased biomarkers of mitochondrial function in preclinical models of aging and in healthy elderly people. UA is a promising strategy to target health and disease conditions of aging, especially those linked to mitochondrial and muscle dysfunction. Urolithin A is better than Rhubarb